Determination of Aristolochic Acids I and II in Brazilian Sugar Cane Spirit Infusions “milhomem†Commonly used in Northeast Brazil as Popular Drinks

Antonio Jorge Ribeiro da Silva

Federal University of Rio de Janeiro, Institute of Microbiology Paulo de Góes, Laboratory of Surface of Microorganisms. Av. Carlos Chagas Filho, 373. CCS Building, block I. CEP 21941-902. Rio de Janeiro, RJ, Brazil.

http://orcid.org/0000-0002-7579-420X

Degree in Industrial Chemistry from the Federal University of Sergipe (1972), Master's degree in Natural Product Chemistry from the Federal University of Rio de Janeiro (1976) and PhD in Organic Chemistry from the Federal University of Rio de Janeiro (1989). He is currently a Full Professor at the Federal University of Rio de Janeiro. Research analytical methodology applied to substances of secondary metabolism of plants. The subject of research is Brazilian medicinal plants, toxic plants and plants used as food. The main focuses of activity are phenolic substances (lignans, arylpropanoids, flavonoids, condensed and hydrolysable tannins). Currently developing the following lines of research: 1. Structure, stereochemistry and conformation of natural products NMR spectroscopy and mass spectrometry. 2. Development of analytical methodology applied to secondary metabolites of plants and 3. Phytochemical analysis of foods. The projects of the research line "Structure, stereochemistry and conformation of natural organic molecules, NMR spectroscopy and mass spectrometry" aim to study structural aspects of natural product molecules such as the determination of spectral correlations used in structural elucidation of these products, study of molecular dynamics through measures of longitudinal nuclear relaxation and also measures of the homo and heteronuclear nuclear Overhauser effect applied to the study of molecular conformation in solution and the evaluation of asymmetric synthesis processes of molecules aiming to determine their absolute configuration. The research line in "Development of Analytical Methodology Applied to Secondary Plant Metabolites" is made up of projects aiming at the application of chromatographic methodology (gas phase chromatography, high performance liquid chromatography, medium back pressure) for the resolution of extracts. obtained from plants and microbes. In this line are developed projects in plant metabolomics under biotic / abiotic stress, as well as the phytochemical study of Brazilian medicinal plants. The research line in "Phytochemical analysis of foods" was introduced as a consequence of the development of partnership projects in the analysis of carotenoids, capsaicinoids, vitamin C in Brazilian Capsicum peppers, in addition to the study of phenolic acids, flavonoids and fruit pigments.

Maria Auxiliadora Coelho Kaplan

Federal University of Rio de Janeiro, Institute of Microbiology Paulo de Góes, Laboratory of Surface of Microorganisms. Av. Carlos Chagas Filho, 373. CCS Building, block I. CEP 21941-902. Rio de Janeiro, RJ, Brazil.

Graduated in Chemistry, BSc. with technological attributions and Lic., by the University of Brazil (1956); Master in Organic Chemistry, MSc., Rural Federal University of Rio de Janeiro (1967); Doctor of Philosophy, PhD, The University of Sussex, England, (1977). Performed 7 postdoctoral internships in the countries: Germany, England, and Switzerland. He is a member of the Brazilian Academy of Sciences. Worked as University Professor teaching courses on: Organic Chemistry and Organic Analysis, Instrumental Analysis; Spectrometric Analysis, Chromatography, Isolation and Purification Techniques of Natural Products, Biosynthesis, Biorganics, Plant Metabolism, Micromolecular Plant Chemosystem in Universities: UFRRJ, UFF, USP, and UFRJ. Since 1981 he has held the position of Full Professor. He is linked to the Center for Natural Product Research, UFRJ, current Institute of Natural Product Research, IPPN, as Professor Emeritus (2010), in full activity, teaching postgraduate courses and developing research on "Chemical Study of Plants. Brazilian women ". She directs research work for postgraduate students and master's students, as well as postdoctoral and undergraduate students. Is your main interest in scientific research directed to Natural Product Research with a special focus on the remaining Atlantic Forest vegetation, within your General Program? "Chemical Study of Brazilian Plants", which involves the following lines: 1. Traditional Phytochemistry / Biological Activity; 2. Phytochemical Methodology; 3. Micromolecular Plant Chemosystematics; 4. Biochemical Ecology: Plant Defense; 5. Organic Chemical Nomenclature; 6. Biological Diversity.

Celuta Sales Alviano

Federal University of Rio de Janeiro, Walter B. Mors Natural Products Research Institute. Av. Carlos Chagas Filho, 373. CCS Building, block H, CEP 21941-902, Rio de Janeiro, RJ, Brazil.

Daniela Sales Alviano Moreno

Federal University of Rio de Janeiro, Walter B. Mors Natural Products Research Institute. Av. Carlos Chagas Filho, 373. CCS Building, block H, CEP 21941-902, Rio de Janeiro, RJ, Brazil.

Davi Oliveira e Silva

Universidade Federal do Rio de Janeiro, Instituto de Pesquisas de Produtos Naturais Walter B. Mors. Av. Carlos Chagas Filho, 373. Prédio do CCS, bloco H, CEP 21941-902, Rio de Janeiro, RJ, Brasil; Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Laboratório de Superfície de Microrganismos. Av. Carlos Chagas Filho, 373. Prédio do CCS, bloco I. CEP 21941-902. Rio de Janeiro, RJ, Brasil.

Possui graduação em Ciências Biológicas: Microbiologia e Imunologia pela Universidade Federal do Rio de Janeiro-UFRJ (2006), MESTRADO em Biotecnologia Vegetal - Decania do CCS - UFRJ (2009) e DOUTORADO em Biotecnologia Vegetal - Decania do CCS - UFRJ (2013). Atualmente é Biólogo na Universidade Federal de Ouro Preto-UFOP onde é responsável por análises em Cromatografia Líquida de Alta Eficiência (HPLC) de amostras ambientais do DEBIO-ICEB III, além de acompanhamento de manutenção de equipamentos analíticos. Tem experiência na área de Microbiologia Aplicada, com ênfase em Pesquisa de novos agentes antimicrobianos, atuando principalmente nos seguintes temas: Cocos nucifera L., Aristolochia cymbifera, Extratos de Planta, Óleo Essencial, Atividade Biológica, Análise Fitoquímica e Análise de Amostras Ambiental.

Péricles Barreto Alves

Federal University of Sergipe (UFS), Department of Chemistry (DQI), Av. Marechal Rondon, s / n, Jardim Rosa Elze, University Campus. CEP 49100-000, São Cristóvão, SE, Brazil.

https://orcid.org/0000-0002-8955-9614

possui graduação em Química Industrial pela Universidade Federal do Ceará (1979), mestrado em Química Orgânica pela Universidade Federal do Ceará (1984) e doutorado em Química pela Universidade Estadual de Campinas (1997). Atualmente é professor titular da Universidade Federal de Sergipe. Tem experiência na área de Química Orgânica, com ênfase em Química dos Produtos Naturais, atuando principalmente nos seguintes temas: óleos essenciais, atividades farmacológicas, óleos para fins industriais por exemplo; ocimum basilicum (manjericão), espectrometria de massas e plantas medicinais.